目的 研究民族药芒萁的化学成分。方法 综合应用硅胶及Sephadex LH-20柱色谱等天然产物化学分离技术进行分离、纯化,结合文献资料、理化性质、1H-NMR及13C-NMR数据进行结构鉴定。 结果 分离得到14个化合物,分别鉴定为:槲皮苷(1),山柰酚-3-O-α-L-鼠李糖苷(2),芦丁(3),金丝桃苷(4),山柰酚(5),槲皮素(6),2-hydroxy-4-methoxy-2′, 3′-benzochalcone(7),豆甾醇(8),环黄芪醇(9),莽草酸(10),原儿茶酸(11),没食子酸(12),β-谷甾醇(13)和胡萝卜苷(14)。结论 化合物1~14均为首次从该植物中分离到。
Abstract
OBJECTIVE To study the chemical constituents of the ethnic drug Dicranopteris pedata. METHODS The compounds were isolated and purified by comprehensive application of silica gel and Sephadex LH-20 chromatography, and their structures were identified on the basis of comprehensive analysis of their physical and chemical properties, NMR data and references. RESULTS Fourteen compounds were isolated and elucidated as quercitrin(1), kaempferol 3-O-α-L-rhamnoside(2), rutin(3), hyperoside(4), kaempferol(5), quercetin(6), 2-hydroxy-4-methoxy-2′, 3′-benzochalcone(7), stigmasterol(8), cycloastragenol(9), shikimic acid(10), protocatechuic acid(11), gallic acid(12), β-sitosterol(13), and daucosterol(14). CONCLUSION Compound 1-14 are for the first time isolated from D. pedata.
关键词
芒萁 /
侗药 /
化学成分 /
槲皮苷 /
山柰酚-3-O-α-L-鼠李糖苷 /
芦丁
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Key words
Dicranopteris pedata /
Dong nationality drug /
chemical constituents /
quercitrin /
kaempferol 3-O-α-L-rhamnoside /
rutin
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中图分类号：
R284
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参考文献
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脚注
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基金
贵州省科技创新人才团队建设项目(2013-4006);贵州省高层次创新型人才培养计划资助项目(2015-4027)
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